Integrative Modelling of Biomolecular Interactions-EMBO

Date: 02/Jul/2018 Time: 09:00 - 06/Jul/2018 Time: 18:00

Cost: Fees are specified on the course website.

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CLICK HERE TO DOWNLOAD THE BOOK OF ABSTRACTS.

Day 1 – 2 July 2018

 

9:00-9:30

Registration, Welcome address (A. Valencia, BSC) & Opening remarks

Alexandre Bonvin

 

9:30-11:00

Lecture: General Introduction to Protein-Protein Interactions

Shoshana Wodak, Marc F Lensink

 

11:00-11:30

Coffee break

 

11:30-13:00

Lecture: Principles of Docking I -Sampling

Paul Bates

 

13:00-14:30

Lunch break

 

14:30-16:30

Practical: UDOCK - Interactive docking system

Matthieu Montes

 

16:30-17:00

Coffee Break

 

17:00-19:00

Participants flash presentations

 

19:00

Welcome drinks and dinner

 

Day 2 – 3 July 2018

 

9:20-9:30

Day briefing

 

9:30-11:00

Lecture: Principles of Docking II - Scoring

Juan Fernandez-Recio

 

11:00-11:30

Coffee break

 

11:30-13:00

Lecture: Information-driven Docking

Alexandre Bonvin

 

13:00-14:30

Lunch break

 

14:30-16:30

Practical: Integrative docking with HADDOCK

Alexandre Bonvin, João Rodrigues

 

16:30-17:00

Coffee Break

 

17:30-19:00

Practical: pyDock

Fernandez-Recio & Jimenes & Diaz

 

18:30-19:00

Visit to Mare Nostrum supercomputer cluster

 

Day 3 – 4 July 2018

 

9:20-9:30

Day briefing

 

9:30-11:00

Lecture: Bioinformatics & Interface Prediction

Raphael Guerois

 

11:00-11:30

Coffee break

 

11:30-13:00

Lecture: Protein-ligand interactions and design

Birte Höcker

 

13:00-14:30

Lunch break

 

14:30-17:00

Practical: Protein-ligand interaction design

Birte Höcker, Horst Lechner

 

17:00-17:30

Coffee Break

 

17:30-19:00

Practical: Scoring docking models using co-evolution

Jessica Andreani

 

19:00-21:00

Poster Session & Buffet Dinner

 

Day 4 – 5 July 2018

 

9:20-9:30

Day briefing

 

9:30-11:00

Lecture: Integration of Cryo-EM data in docking

Matteo Dal Peraro

 

11:00-11:30

Coffee break

 

11:30-13:00

Lecture: Integrative structure determination of macromolecular assemblies

Maya Topf

 

13:00-14:30

Lunch break

 

14:30-16:30

Practical: Integrative structure determination of macromolecular assemblies

Maya Topf, Sony Malhotra

 

16:30-17:00

Coffee Break

 

17:00-18:30

Practical: Bring your own problem & CASP-CAPRI

 

18:30-19:30

Lecture: Interactomes & Disease

Patrick Aloy

 

19:30- …

Free time

Travel to dinner location

 

21:00

Course Dinner

 

Day 5 – 6 July 2018

 

9:20-9:30

Day briefing

 

9:30-11:00

Lecture: Structure Determination of Genomes

Marti-Renom

 

11:00-11:30

Coffee break

 

11:30-13:00

Lecture: Elastic network modelling in the study of macromolecular assemblies

Turkan Haliloglu

 

13:00-14:30

Lunch break

 

14:30-16:30

Practical: Binding affinity prediction

Iain Moail

 

16:30-17:00

Coffee break

 

17:00-18:00

Q&A/Round Table: Challenges in the docking field

 

18:00

Departure